Zero‐order switches and developmental thresholds

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Zero-order switches and developmental thresholds

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A long-standing problem in developmental biology, closely associated with pattern formation, is how continuous morphogen gradients are translated into sharp response borders that define clearcut territories in which cells express different sets of genes. To understand how gradients can generate thresholds, several mechanisms have been investigated over the years. Initially, most of these studie...

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ژورنال

عنوان ژورنال: Molecular Systems Biology

سال: 2005

ISSN: 1744-4292,1744-4292

DOI: 10.1038/msb4100042